How to Make Liposomal Essential Oils at Home: Ultrasonic Method Tutorial

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Tutorial:  How to Make Four Ounces of Liposomal Peppermint Oil (LEPO)
Updated 6/17/2017

This tutorial is designed to teach the “home brewer” how to make high quality liposomal essential oil formulations.  It does not cover how to use them.  This tutorial utilizes the ultrasonic encapsulation method, as apposed to using the blending method.  The essential oil used is peppermint.  Liposomal peppermint oil is one of the easiest formulations to make.  It is very stable, and has a greater shelf life than many other liposomal essential oils (EOs).  Furthermore, it is currently being studied for its strong antimicrobial properties.

The same general procedure can be used to create other liposomal essential oils, or even essential oil blends.

What is a Liposome? …and Why Encapsulate Essential Oils?

What is a liposomal formulation?  In our case, it is a colloid made up of spherical phosphatidylcholine particles that exist in a water medium.  Inside the lipid (fat) particles, the “substance of choice” is  encapsulated — surrounded– by the spherical  particles.  In essence, the encapsulated substance (in this case, peppermint EO) exists inside of the lecithin, which is suspended in colloidal form within the water.

The official definition:  “An artificial vesicle composed of one or more concentric phospholipid bilayers and used especially to deliver microscopic substances.”

Liposomes are nature’s perfect bio-delivery system.  What is the best natural liposomal formulation?  Easy:  Breast milk!

Essential oils are not water soluble, and they are not very bio-available.  Furthermore, they cannot be diluted down for easy and safe in water.  However, once in liposomal form, they become completely bio-available.  Furthermore, you can dilute one drop of liposomal essential oil (LEO) in as much water as needed.  The LEO will completely disperse in the water.  You can even add one drop of LEO to a gallon of water, and it will disperse evenly throughout the whole gallon.

Supplies Needed

Supplies Needed

Links to products are provided (Amazon) as necessary.  If no link is provided, then simply choose your own personal preference.

  1. An ultrasonic bath/cleaning unit:  iSonic P4830 Commercial Ultrasonic Cleaner
  2. 1/4 ounce of organic peppermint essential oil or CO2 extracted peppermint oil
  3. Phosphatidylcholine:  In this case, non-GMO Soy Lecithin: Lecithin Granules
  4. One 5 ounce measuring glass container: 5 Oz Glass Measuring Glass
  5. 4 ounces of colloidal silver (or distilled water)
  6. A small amount of grain alcohol (40-50 Proof)
  7. A sensitive digital kitchen scale (.001 grams): MilliGram Scale, 20 by 0.001 G
  8. Two small measuring cups (1 ounce)
  9. A way to measure water temperature (a laser temperature meter): Digital Infrared Thermometer Dual Laser
  10. One four ounce glass dropper bottle
  11. A stirring rod

Getting Started

Making liposomal essential oils is actually very easy.  EOs lend themselves to encapsulation very well.  In fact, it only takes about 1% phospho-lipids to get the job done.  Furthermore, the process is very forgiving.  In the event of error, one simply needs to add a bit more lecithin or essential oil.

There are two simple secrets to making the perfect “liposphere”:

1.  Use 1-10% grain alcohol (40 or 50 proof) by weight.  The grain alcohol immediately separates the lecithin particles, and helps to prevent clumping.

2.  Heat the formulation while encapsulating.  Heating the lecithin changes the permeability of the lecithin, allowing easier penetration of the essential oils.  Lecithin is actually very heat resistant at the temperatures we will be using.

While, as stated above, it only takes about 1% lecithin to essential oils used, different essential oils may require slightly different amounts of lecithin.  Sometimes, one may need to add just a bit more lecithin in order to encapsulate all of the essential oil.  It’s easy to tell when more lecithin needs to be added.  After processing the brew in the ultrasonic cleaner, a “puddle” of essential oil will pool on top of the water.  If this happens, simply add a bit more lecithin and reprocess.

If you don’t have access to a good scale, you can always “eyeball” the amount of lecithin to use.  The images in this tutorial will give you an idea of how much is needed:  Not very much!

Preparation

  1.  Measure out the essential oil.  For a four ounce bottle, 1/4 ounce of peppermint oil will be needed.
  2. Weigh the essential oil in a small measuring cup.  Use grams if possible.  Make a note of the weight.  The weight will be used to calculate the amount of lecithin required.
  3. Pour the essential oil into the 4 ounce glass container.  This container will be used to process the liposomal peppermint oil in the ultrasonic bath unit.
  4. Calculate the amount of lecithin to use by multiplying the weight of the essential oil by .01 (one percent).
  5. Using a second measuring cup placed on the scale, measure out the required amount of lecithin.  Then, pour the lecithin into the 4 ounce glass container that currently contains the peppermint oil.
  6. Add between 1 and 12 ml of the grain alcohol into the 4 ounce glass container.  Watch how the lecithin immediately begins to separate the lecithin particles (a small amount of the lecithin will have already dispersed in the water).
  7. Add about one ounce of colloidal silver (or distilled water).

Measuring the Essential Oil:  In this case, 5.82 grams

Measuring the LecithinMeasuring the Lecithin: 1% of the Essential Oil, by Weight
In this Case, 0.05 grams

Glass Container with all Ingredients:  Ready for the Ultrasonic Bath

Process the Liposomal Formulation in the Ultrasonic Bath

Ultrasonic Bath - Essential Oils - PeppermintEncapsulating the Peppermint Essential Oil:  Notice the Color Change

Now, prepare the ultrasonic bath for operation exactly as described in the device’s manual.  Place the 4 ounce glass container on the rack in the center of the ultrasonic bath.  The bath that we recommend purchasing can be run for 30 minutes at a time.  It also has a heater, which is important.

Turn the heater on, set the ultrasonic timer for 30 minutes and press start.  During this process, stir the LEO every so often.  It is also wise to check the temperature after 15 minutes, although the target temperature usually will not be reached until the second run of the ultrasonic bath.

Once the timer runs out, repeat the above process.  Set the timer for 30 minutes, and be certain that the heater is on.  Keep in mind that the heater is on a auto shut off timer.  If you are uncertain how long the heater has been running, simply turn it off and on.  This time, check the temperature of the formulation at the ten minute mark, and every five minutes afterward.  Once the temperature reaches between 105 degrees F and 115 degrees F, turn the heater off.  Allow the ultrasonic bath to finish its cycle.

Observe the surface of the “water” very carefully.   You should see a layer of melted lecithin on top.  This surface layer of lecithin will be rich with essential oils, and it is completely normal.  However, if there is a layer of pure essential oil separated from the lecithin, more lecithin is needed.  Simply add a bit more lecithin, and process the batch again for 30 minutes.  Once again you can heat the formulation up to between 105-115 degrees F if necessary.

Note that all of the liposomal peppermint oil beneath the top lecithin layer is completely white!  When liposomes are fully dispersed in water, they are always white.   When there is lecithin that doesn’t disperse in water due to concentration levels, the color is yellowish-orange.  When this lecithin is diluted in more water, then the color should change to white, indicating a proper formulation.

If no separated essential oil is floating on the surface, the ultrasonic bath is no longer needed.  You are done processing.

Fill the glass container up to the 4 ounce mark with colloidal silver (or distilled water), and mix well.

Transfer the completed LEPO into the 4 ounce glass dropper bottle.  Only make what you plan on using, and always refrigerate LEOs when not in use.  Different liposomal essential oils will have different shelf lives.  That said, liposomal peppermint oil and liposomal Ceylon cinnamon oil are both very stable and resist degradation more so than many other types of LEO.

More information, including a commentary and more FAQs, will be added in the future!

Liposomal Peppermint Essential Oil (LEPO)Liposomal Peppermint Essential Oil – After the Ultrasonic Bath Encapsulation Process
Last Step:  Add Colloidal Silver/Water to complete the 4 Ounces, then Bottle and Refrigerate

FAQ

Isn’t there a way to make the formulation so that there is no top layer of lecithin once complete?

Yes, absolutely.  However, doing so will result in dosing difficulties.  With this method, 16 drops of the essential oil is the equivalent of one drop of pure essential oil.  Making a more concentrated formulation works perfectly, and is much more convenient to store and use.  Furthermore, if you don’t need precise dosing information, you can take that top layer of lecithin, and add it to coconut oil to make a fantastic lipid-rich essential oil cream for topical use.

Can the blender method be used in place of the ultrasonic method?

Yes.  However, keep in mind that any time you use a blender, you are greatly increasing oxidation, and you do not have any control over the heating.  Furthermore, you would most likely have to use a dedicated blender for this process.  It is difficult to get the smell of essential oils out of plastic.

The ultrasonic method creates a superior product to blending, despite rather loud voices claiming otherwise.

I see quite a few very affordable ultrasonic cleaners available for purchase online.  Why can’t I purchase one of the cheap ones?

If you can find an affordable ultrasonic cleaner with the right specifications, feel free to get one!  Please keep in mind that most of the “cheap” models have a maximum run time of about five minutes.  Furthermore, many of the affordable models do not have heating elements.  If you plan on actually making liposomal formulations, you really need a machine that can run uninterrupted for 30 minutes.  A unit that has a heating element is also important.

Can I use a different type of cinnamon?  I have access to very affordable oils.

Please ONLY use Ceylon cinnamon bark oil.  By using other types of cinnamon oil, you risk causing serious liver damage.

Can I use Ceylon cinnamon leaf oil?

For this tutorial, please use Ceylon cinnamon bark oil.  Once you are familiar with the process, you can diplicate it using any essential oil that you’d like, at your own discretion.

Why does this process only take an hour of ultrasonic processing?  When making liposomal vitamin C, the recommendation is to process for much longer, refrigerating the formulation between ultrasonic sessions.

Essential oils, when combined with lecithin, almost encapsulate themselves without effort.  Essential oils lend themselves to encapsulation very easily, since they are non-water soluble solvents.  There is no need to over-process them, although it will not hurt if they spend more time in the ultrasonic bath.

Some companies make a gel, not a liquid.  Should I be making a gel instead?

NO.  Studies published are conflicted about the true efficacy of liposomal formulations.  The main reason:  In order for a formulation to be highly effective, the lipids MUST separate into their “spherical” liposomes.  Furthermore, when used internally, liposomal formulations should be taken with a lot of water.  At least eight ounces.  This will dilute stomach acid and allow the liposomes to be absorbed into the body intact.

In the tutorial, you use lecithin derived from soy.  Can another form be used?  How about lecithin derived from organic sunflower seeds?

Please keep in mind that lecithin derived from soy is completely devoid of the protein that causes issues in the human body.  That said, it is difficult to find organic soy lecithin compared to organic sunflower lecithin.  However, it may be surprising to realize that tolerance to the soy lecithin is better.  If you use sunflower lecithin, and have tolerance issues, it’s probably due to the lecithin.

Furthermore, the highest quality product to use a special, balanced form of lipids, where the ratio between omega 3’s and omega 6’s is perfect.  This product is also expensive.  This product is the product that I personally usually use in place of lecithin to make liposomal formulations:

http://www.bodybio.com/storeproduct426.aspx

Will this process make nano liposomes?  Should I add another emulsifying agent?

YES.  This process will make liposomes on the small end of the nano liposome spectrum.  However, it is not a guarantee that all of the liposomes will be uniformly sized, as there is no process in place to ensure that only nano lipids are formed.  That said, this method, especially with the “gentle heat” and use of grain alcohol, is the superior process to use outside of a very expensive lab setting.

No, there is no need to add any other emulsifying agent.  The following is a quote from Hielscher.com, a manufacturer of ultrasonic technology:

“…Ultrasound is a proven method of liposome preparation and the encapsulation of active agents into these vesicles…”

“…Regarding to their composition and size, one differs between multi-lamellar vesicles (MLV, 0.1-10μm) and unilamellar vesicles, which are distinguished between small (SUV, <100 nm), large (LUV, 100–500 nm) or giant (GUV, ≥1 μm) vesicles. The composite structure of liposomes consists of phospholipids. Phospholipids have a hydrophilic head group and a hydrophobic tail group, which consists of a long hydrocarbon chain. The liposome membrane has a very similar composition as the skin barrier, so that they can be easily integrated into the human skin. As the liposomes fusionate with the skin, they can unload the entrapped agents directly to the destination, where the actives can fulfill their functions. Thus, the liposomes create an enhancement of skin penetrability/ permeability for the entrapped pharmaceutical and cosmetical agents. Also liposomes without encapsulated agents, the vacant vesicles, are potent actives for the skin, as the phosphatidylcholin incorporates two essentials, which the human organism cannot produce by itself: linoleic acid and choline. Liposomes are used as biocompatible carriers of drugs, peptides, proteins, plasmic DNA, antisense oligonucleotides or ribozymes, for pharmaceutical, cosmetic, and biochemical purposes. The enormous versatility in particle size and in physical parameters of the lipids affords an attractive potential for constructing tailor-made vehicles for a wide range of applications. (Ulrich 2002)

“Ultrasonic Liposomes Formation Liposomes can be formed by the use of ultrasonics…”

“…To enhance the nurturing effect of moisturizing or anti-aging cremes, lotions, gels and other cosmeceutical formulations, emulsifier are added to the liposomal dispersions to stabilize higher amounts of lipids. But investigations had shown that the capability of liposomes is generally limited. With the addition of emulsifiers, this effect will appear earlier and the additional emulsifiers cause a weakening on the barrier affinity of phosphatidylcholine. Nanoparticles – composed of phosphatidylcholine and lipids – are the answer to this problem. These nanoparticles are formed by an oil droplet which is covered by a monolayer of phosphatidylcholine. The use of nanoparticles allows formulations which are capable to absorb more lipids and remain stable, so that additional emulsifiers are not needed. Ultrasonication is a proven method for the production of nanoemulsions and nanodispersions.”

What is the shelf life of liposomal essential oils?  If the oils that I use are antimicrobial, shouldn’t they preserve the formulation?

Assume that the refrigerated shelf life is 60 days.  The actual shelf life will depend on many factors, including how much lecithin is used, and the exact properties of the essential oil(s) used.

The issue with liposomes:  Most of the EO will be encapsulated.  It is impossible for the EO to be in contact with all of the lipids all of the time.  Lipids are great food for both humans and microbes.  There is plenty of open surface area where essential oils and colloidal silver cannot act as preservatives.  This is why liposomal formulations must be refrigerated and “made to use” only.

There are exceptions to the rule.  Liposomal peppermint oil and liposomal ceylon cinammon bark oil both resist bacterial and fungal growth very well.

That said:  Safety first!

Is it really worth the equipment investment?  Are liposomal formulations that good?

If you love essential oils, or if you want to be on the cutting edge of alternative medicine, then:  Yes.  You are not limited to making essential oil liposomal formulations.  My favorite liposomal formulation for detox (advanced):  Alpha lipoic acid, NAC, glutathione, and vitamin c.

Why liposomes, exactly?

1. Using lipids to encapsulate essential oil makes the essential oils water soluble. This makes managing concentrations MUCH easier.

2. Recent studies done with Bergamot demonstrate that essential oils used internally “as they are” are not bio-available enough to be truly effective (in this case, targeting cancer cells). Liposomes are nature’s finest bio-delivery system (breast milk is liposomal).

3. The lipids help protect the encapsulated EOs from the external environment.

4. The body recognizes phosphotydalcholine (and other lipids) as actual food. All human cells require it.

5. Liposomal formulations mix very well with other substances for topical use.

Commentary

This tutorial doesn’t delve into the use of liposomal essential oil formulations.  If you are interested in more specific liposomal formulations, please let me know by commenting below.  I have quite a few amazing advanced liposomal formulations from Eytons’ Earth – Private Stock!

Outside Resources

http://www.ncbi.nlm.nih.gov/pubmed/24099646

Abstract: In-vitro study of the effectiveness of liposomal bergamot essential oil on cancer.

http://www.curezone.org/blogs/fm.asp?i=1735341

Inhibiting and degrading biofilm using the most effective essential oils.

http://www.sciencedirect.com/science/article/pii/S0166354298000345

Abstract: Some biochemicals found in essential oils exhibit strong anti-viral capabilities

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941848/

Abstract: Exploring the antifungal effects of liposomal essential oil (eucalyptus)

http://www.realnatural.org/liposomal-encapsulation-of-tea-tree-boosts-its-antibiotic-potency/

Liposomal tea tree oil and silver ions yield improved antimicrobial activity without the possibilty of the microbes developing a resistance.

http://www.eytonsearth.org/liposomal-essential-oils.php

…an example of a complex liposomal essential oil formulation:  Antimicrobial blend.  Please note that this formulation is no longer commercially available.

https://www.hindawi.com/journals/ecam/2014/651593/

This is a fantastic journal article written for “Evidence-Based Complementary and Alternative Medicine”, Volume 2014 (2014), Article ID 651593.  The article is entitled “Essential Oils Loaded in Nanosystems: A Developing Strategy for a Successful Therapeutic Approach”.  This article gives a great overview of essential oils in general, and specifically… section 4… deals with nano encapsulation.  Note that the article states that LEOs are not only more bio-available, but also likely more bio-effective.

Furthermore, the authors state:  “It is accepted that topical drug delivery with nanoparticles targets the nanoparticles into the deeper layers of skin and generally they do not reach the viable epidermis. Only where the cheratine barrier is compromised, however, such as in aged or diseased skin, an enhanced particle penetration occurs. The use of nanoparticles provides a sustained and slow release of the active constituents; nanoparticles represent a reservoir. “

The authors are also quick to point out “Particle size, shape, and surface properties of the nanoparticles play a crucial role in the uptake of nanosized delivery systems across the mucosal membrane. The nanocarriers with particle size of 50–300 nm, positive zeta potential, and hydrophobic surface were found to have preferential uptake as compared to their counterparts.”

The methods and materials we use produce a wide range of extremely small particles, which are ROUND IN SHAPE.  The round particles prevent cytotoxicity otherwise commonly associated with nanoparticles below the 40 NM range.  The PC used to create the liposomes (from the lecithin) are the absolute ideal delivery system.

Be sure to check this article out!

 

Summary
How to Make Liposomal Essential Oils at Home: Ultrasonic Method Tutorial
Article Name
How to Make Liposomal Essential Oils at Home: Ultrasonic Method Tutorial
Description
Learn how to make LEOS: Liposomal essential oils. This tutorial explains how to make liposomal peppermint essential oil using the ultrasonic method.
Author
Publisher Name
Eytons' Earth
Publisher Logo

23 thoughts on “How to Make Liposomal Essential Oils at Home: Ultrasonic Method Tutorial”

  1. Jason is there a less expensive ultrasonic cleaner that ca be used instead of the iSonic?
    Thank You for your help

    1. Hi Dennis:

      …you can try to find one!

      The two important features that many of them lack:

      1. The heating element

      2. Most will only run for 5 minutes or so at a time. This means that you’d have to keep resetting the unit over and over again.

      If you find a good one cheaper, please let me know!

  2. Is there an alternative/ substitute I can use for the grain alcohol?

    I think my digestive track has trouble tolerating tinctures. I do not think I can take meds with alcohol in them anymore. I had been making tinctures with grain alcohol, but lately that has not been working so well for me.

    1. Hi Tracy:

      You can simply omit the grain alcohol if necessary. It is certainly possible to become sensitive to grain alcohol. Some people cannot tolerate it at all.

      You will still get liposomal essential oils, but the liposome particle sizing won’t likely be as minute. This not a real issue, considering that many people make liposomal products simply by blending things with phospho-lipids. The refined process simply allows one to make a higher quality end product.

      If you want to try to stabilize the nano lipisomes created with ultrasound… without the use of grain alcohol… you can experiment with adding glycerin and synthetic vitamin e (Tocopherol). However, I have not yet calculated the amounts to use, so you’d have to experiment! I most likely will be incorporating glycerin and Tocepherol in my own personal formulations to help stabilize the nano sized liposomes.

      Some people cannot tolerate it at all. BTW: There is a method to remove alcohol from tinctures using gentle heat and a a grain alcohol alcohol hydrometer.

      ~Jason

  3. Hi Jason Thanks for the quick reply. That is great. I’ve begun to make glycerites since this started happening, so its good to know there are other options when it comes to liposomal essential oils. I read there was a way to remove grain alcohol for pets who cannot not tolerate alcohol. I thought it was complicated. I will look into getting a grain alcohol hydrometer. I have a lot of tinctures. I hope they are not too expensive. Thanks again 🙂

    1. Hi Tracey:

      You are welcome!

      Here is a link to an alcohol hydrometer on Amazon (it’s under $7.00):

      Grain Alcohol Hydrometer

      Depending upon the herbs and the amount, it can take 4 to 12 hours to rid tinctures of the alcohol.

      Simply pour your tincture into a wide-mouth glass jar or measuring glass. Use very low heat as to not destroy the properties of the herbs. I use a little fan blowing on the surface to speed the process up.

      If your tincture is 50/50 (100 proof), then simply evaporate the tincture down by about half. When you think you are done, use a tall and THIN graduated glass cylincer (100 ML is usually ok)… pour the tincture into the cylinder a little over half way. Then, insert the glass hydrometer. If all of the alcohol is gone, it will read “0”. If it rises “above the line” you still have some alcohol to evaporate off.

      When are done, add some purified water back in to return the tincture to its original strength. Remember, that with the alcohol now gone, refrigerate your tincture and keep in mind that it will have a short shelf life!

      Here is a link to the glass cylinder I use to test samples… and to ozonate a small amount of olive oil! 🙂
      100 ml Glass Cylinder

      Kind Regards,

      Jason

  4. Hi Jason,

    Thanks for the follow up directions. I was worried about destroying the medicinal properties of the tincture.

    It’s funny you mentioned ozonated olive oil. I am in the process of cleaning my garage so that I can find mine. Wish I was not such a pack rat. 🙂

    Thanks

  5. Hello Jason. Thank you for your research and generosity. I had a thought. Those not accustomed to weighing out ingredients on a scale, may not know about “tare”.
    To “tare” is to place your container on the scale and subtract its weight by pressing the “tare” button on the scale. A simple thing, but very necessary in order to get correct weights. I do not know if there are self tareing scales?
    I have become lazy about making my liposomals. This has re-inspired me!

    1. Hi Mary:

      Good point! When I update the article, I’ll add this info. Until then, hopefully people either read the comments, or their instruction manuals!

      …You are welcome. I have noticed that I research in spirals. I’ll finish a project and start work on another research project. Then, finally, I come full circle, and get inspired to return to a given project. Usually, the “inspiration” is “coincidental”, but it always seems to result in a major personal breakthrough.

      With each “return”, I gain so much more depth perception into the subject matter… deeper and deeper. The new understanding from project “A” usually “magically” lends itself nicely to the next project, the next inspiration.

      Sometimes, it even seems like I’m not the one making the choices. 🙂

  6. Hi Jason:

    I tried your recommendation of using Glycerine and Vitamin E to replace the alcohol to stabilize the nano liposomes. You were right about the particle size. … but it worked. I was wondering what you thought about using Sodium Alginate and chitosan. Before I found your post, I found numerous experiments on essential oils in which those two ingredients were used with sonication. I read that Sodium Alginate is a natural polysaccharide product extracted from brown seaweed that grows in cold water regions. It is soluble in cold and hot water with strong agitation and can thicken and bind. In presence of calcium, sodium alginate forms a gel without the need of heat. I read that Chitosan is a sugar that is obtained from the hard outer skeleton of shellfish. I cannot figure out why they used that. I found this combination in numerous studies.

    What do you think?

    1. Hi Tracey:

      I haven’t yet worked with either substance, but certainly the Sodium Alginate should work. When you add other sugars and “fats” to the mix, you’re reducing the number of PC liposomes, and this will likely change how the body utilizes them. That said, who knows if it would be a reduced, improved, or the same end effect. I personally like the type of formulation as this tutorial presents, because it is then very, very easy to get the liposomes separated “in solution”. If a gel is too thick, it can reduce absorption, which is why some studies on liposomal formulation do not show an improved biological effect like one would expect. Nano encapsulation is only relevant if at some point the liposomes separate independent of biochemical reactions.

      However, conversely there may be a benefit to using a more gel-like formulation. This might reduce the amount absorbed, but the gel would coat the digestive tract as it is digested.

      You could further DECREASE the systemic effect and increase the effect in the digest tract by incorporating something like castor oil.

      …lots of creativity left to be explored.

      As far as chitosan, I know that NANO chitosan is being studied for its anti-pathogenic effects.

  7. PS. I am looking at alternate formulas because I would like to do this with herb extracts and I am having trouble finding Vitamin E that is considered safe for consumption.

    Tracey

  8. Hi Jason. I appreciate you insights and responding so quickly. Really Interesting information about Nano chitosan. Thanks. this i just in case I can’t find more Vitamin E that does not say do not consume on the bottle. Wish I could just do the grain alcohol formula.

    Another question. I wanted to do the same with herbs. do you think glycerin could be an acceptable substitute for the alcohol?

    I am leery because when I tried to switch from making tinctures with alcohol to glycerites, many were not that strong. I was tincturing a lot of Chinese medicine herbs which uses a large number of roots. So now the plan is to tincture with alcohol, boil of the alcohol, and now I am considering adding glycerine and and a preservative like potassium sulfate (vitriolated tartar) or some other preservative. I guess I have to determine that they are safe and will not effect the liposomes.

    bearing in mind what you wrote about adding other sugars and “fats” to the mix, I guess that would eliminate potassium sorbate since it is a fatty acid.

    Also, do you know of a source of consumable vitamin E because I really did like how my lyme formula turned out? If I could stick with vitamin E that would be great

    Sorry about all the questions. thanks for sharing you

    1. Hi Tracey:

      I think that you are on the right track. You are absolutely correct about alcohol tinctures being far stronger than anything else.

      I would go ahead and make the alcohol tincture, then evaporate the alcohol off, and then combine it with glycerin…and alpha-tocopherol if possible/desired. This is a synthetic vitamin e, but it appears to be safe to use, especially since you’d only be using it to take advantage of its unique property as a water and fat soluble medium. Dr. Christsopher Shade uses it, and his knowledge of biochemistry is extensive. His formulations are pain staking as far as attention to detail and efficacy goes.

      As far as preservatives go, I don’t use them. I refrigerate my brews after removing the alcohol.

      That said, things like potassium sorbate/sulfate can be used, if absolutely necessary.

  9. Gosh you are fast. This is great news! Trader Joes has a Vitamin E I can use. That was my block.

    Understand your sentiment about preservatives. Because so many people in my family are ill, we have very little food in the house with preservatives. Maybe cheese……I basically feel the same, but got nervous because some of my first batches of glycercites– celery seed, turmeric/ pepperine, and maca molding in less than a month. I realize it was likely that I did not stick to the rule about making sure that your ratio of glycerine to water is more than 50% glycerine. All my other batches have been fine. I was looking for another solution because I have been tincturing, juicing and fermenting like crazy. Now I am adding liposomoals and I may have to start making raw dog food for my dog. (He is sick too. We are running out of room in the frig. We have been talking about getting a frig to put in the garage. I guess I may have too.

    PS. made your cabbage ferment. YUCK!! :-). HOWEVER, my husband has made taking it a nightly family ritual in which we all take it together enduring that interesting taste as a group…. looks pretty though

    PPS. two a second look after MSM after reading your article. Found that it was could not only for collagen but nerve damage as well.

    I love your posts.

    Thanks again

    1. Hi Tracey:

      Just keep in mind that the synthetic vitamin e has different properties then natural vitamin e, as far as vitamin e’s ability as an emulsifier. I’m not sure how great the difference would be.

      If you stick with the cabbage juice, eventually your taste buds will change. 🙂

      MSM can be really amazing even though high dose MSM therapy is a bit controversial. Sometimes you have to use a lot to get the job done.

      I also recommend that you take a look at my most recent blog post, not just for hydrating therapeutic clay, but for making very high quality salt soles. I think that almost everyone should be taking at least 1 tsp daily of the highest possible quality salt sole. I haven’t found anything to replace it… which is probably why Raymond Dextreit lists sea salt as one of the seven irreplaceable healing substances on the planet. For those in digestive system failure where nothing else has seemed to get the job done, a person might try taking 1-3 tsp. of nine times roasted bamboo salt daily, while also drinking plenty of water throughout the day.

      ALSO…. not that you need any more work to do…BUT… since you are already proficient at making LEOS, I suggest that you look into making Para Rizol Zeta. This is a hammer! I wrote a tutorial here:

      http://www.silvermedicine.org/lipozinoil-para-rizol-zeta.html

      …I also have written tutorials on how to make ozonated olive oil and ozonated castor oil specifically to make rizol with… BUT, it is time consuming and requires specialized equipment. You can always buy the ozonated olive oil and the ozonated castor oil, and then make the rest yourself.

      This stuff stays bio-active where ever it is used for at LEAST 12 hours. Super sick animals or people might consider using it as a suppository, building up to a standard does of one whole ounce.

      You don’t have to use the essential oils recommended in the formula, of course. You can make your own. Simply get the same amount of oils in the end formula, and don’t leave out the Walnut oil. 🙂

  10. Hey Jason:

    So I rambled on so much, you missed my main question. If I want to use the liposomal process with herbs and cannot not use the alcohol, what should I do? Do I use the Glycerine and Vitamin E?

  11. Hi Jason: i promised myself I was going to stop bugging you today, but then you posted all this great information. So more questions. if you do not feel like answering, I won’t be offended.

    We’ll see about the cabbage becoming palatable. :-). I hope so.

    I think I remember doing high does of MSm in the past. I was also pulsing really high doses of vitamin D with good results. I why is it controversial? The on>ly reason why I stopped is I read that it could make migraines worse and after my alcohol problem, I was worried about my digestive track. What are the contraindications, or is it like with Vitamin D,.. just a misinformed medical community.

    I’ve been meaning to check out your clay. I used it twice with great success to repair my digestive track. Since the grain alcohol fiasco, I started taking it again.

    Funny you mention ozone, I was just in my garage cleaning it out partially tofind my ozone machine. No luck. 200 rounds of chemo left me unmotivated for a long time and now it is a big closet, but I will persevere. my memory of Ozonated olive oil making was that it is very complicated process, so I used to buy it. In fact, I still have some ozonated olive oil and cococut oil in the frig, but it is very old, so i do not know whether it still has its potency.

    I was very ill with severe cognitive issues when I tried to make it before. my brain is mostly recovered so when I find the ozone machine, I will give the Para Rizol Zeta a try. I had a lot of success with ozone theraphy. It is funny that you mentioned Castor oil, I will just research how to ferment Wheat Germ and Castor oil. I am hesitate, because I am a whim and I am scared to ingest. However, I will likely peruse it after I learn how to use the tincture percolator I just make. My brain it about to burst trying to learn how to do all this stuff. My husband now calls our house the apothecary.

    Regarding the essential oil formukla, I did not see the how to take essential oils post, until after I made mine. I really like it. Most of them are listed as being effective as liposomals in treating lyme, so as soon as I finished this batch, I was going to try your formula and add one more … yarrow into it.

    Regarding suppositories, I had been trying to convince my teen daughter to use this approach, but I did not consider using it on my dog. I thing he has something called Pemphigus Foliaceus cause by a vaccine he received when he was a puppy. He mostly takes the capsules I give him and he loves turmeric, ghee and yogurt, but the Ayurveda formula I was using stopped working, so I am looking at chinese medicine and I am afraid that it would require too many capsules. Making an extract and putting it in a suppository might work. it is a great idea.

    I will definitely try roasted bamboo salt. I’ve been having suggest with dragon’s blood, D- Limonene, papain, mastic gum, noni, slippery elm, marshmallow root, and Golden Thread. It is working, but the faster me and my daughter can recover from this digestive crisis the better. Do you sell it on your clay site or do I buy it elsewhere?

  12. Did not see any of the bamboo salt in your store, but I read your article on making Himalayan and Bamboo Sole and saw the specific brand you recommended there and purchased some on Amazon as you referenced in the post.

    read that you will be offering in the future. I will check back the next time I need some to see if you have begun selling it.

    Thank again

    1. Hi Tracey:

      Thank you, that is appreciated!

      Yes, I’m still in the process of finishing testing the Bamboo salt.

      We will most likely be selling it in 1 kg. containers (bulk).

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